Guy Haskin Fernald

Contact Information
3976 25th Street Voice: (415) 642-1727
San Francisco, CA 94114 Fax: (650) 745-3216
Web: www.guyhf.com
Email: guy@guyhf.com

Research Interests Integrated systems pharmacology for the prediction of pharmacological phenotypes, pharmacogenes, and drug repositioning.

Education

Stanford University
Stanford, California Current

Ph.D candidate in Biomedical Informatics, Master's of Science in Medicine candidate.

UC Berkeley Extension
Berkeley, California2004

Classes in microbiology and bioinformatics.

City College of San Francisco
San Francisco, California2003

Classes in biology and chemistry. Laboratory work in PCR, recombinant DNA, and gel electrophoresis.

Swarthmore College
Swarthmore, Pennsylvania1994

Bachelor of Arts. Majors: Mathematics and Computer Science. Additional courses at the University of Edinburgh.

Honors and Awards

  • National Science Foundation GRFP Honorable Mention, 2009.
  • National Library of Medicine Training Grant Recipient, 2008.
  • Phi Beta Kappa, 1994.
  • Bachelor of Arts awarded with Distinction, 1994.
  • Nasa Ames Group Achievement Award, 1990.

    • Publications

    Fernald GH, Capriotti E, Daneshjou R, Karczewski KJ, Altman RB. Bioinformatics Challenges for Personalized Medicine. Bioinformatics (2011) 27 (13): 1741-1748.

    Tatonetti NP, Fernald GH, and Altman RB. A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports. J Am Med Inform Assoc. 2011 Jun 14.

    Tatonetti NP, Denny JC, Murphy SN, Fernald GH, Krishnan G, Castro V, Yue P, Tsau PS, Kohane I, Roden DM, and Altman RB. Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels. Clinical Pharmacology and Therapeutics (2011) 90 1, 133–142.

    Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, Ousman SS, Fernald GH, Gerlitz B, Robinson WH, Baranzini SE, Grinnell BW, Raine CS, Sobel RA, Han DK, Steinman L. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature. 2008 Feb 28;451(7182):1076-81.

    Fernald GH, Pachner A, Caillier S, Narayan K, Oksenberg JR, Baranzini SE. Genome-Wide Network Analysis Reveals the Global Properties of IFN-beta Immediate Transcriptional Effects in Humans.J Immunol. 2007 Apr 15;178(8):5076-85.

    Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini SE. 2005. Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis. J Neuroimmunol 167(1-2):157-69.

    Conference Presentations Fernald GH, Tatonetti NP, Altman RB. 2010. A Systems Biology Method for Predicting Drug-Gene Interactions in Saccharomyces cerevisiae, P-STAR Conference, Memphis, TN.

    Fernald GH, Pachner A, Caillier S, Narayan K, Oksenberg JR, Baranzini SE. 2006. Network-based analysis unveils global properties of IFNΒ immediate transcriptional effects in humans. International Conference on Complex Systems. Boston, Massachusetts.

    Poster Presentations

    Fernald GH, Tatonetti NP, Altman RB. Generating Credible Hypotheses for Drug-Drug and Drug-Gene Phenotypes. NLM Bioinformatics Training Program Conference, June 2011.

    Fernald GH, Tatonetti NP, Altman RB. A Systems Biology Method for Predicting Drug-Gene Interaction in Saccharomyces cerevisiae. BCATS 2010.

    Fernald GH, Tatonetti NP, Altman RB. PharmReduce: A Symmetric Framework to Rank Pharmacogenes, Phenotypic Effects, and Small Molecules. BCATS 2009.

    Patents Adams N, Brown M, Carlstrom B, Elkin B, Hegarty P, Haskin G, Putanec B. Operating resource management system. US Patent no. 7,117,165, October 3, 2006.

    Professional Experience

    University of California, San Francisco Research Associate
    San Francisco, California 2004 - 2007

    Investigated the role of genetic linkage and gene expression in multiple sclerosis and experimental autoimmune encephalomyelitis through statistical methods, network analysis, and computer modeling with the use of high performance computing and distributed processing.

    Instituto National de Salud Publica
    (National Public Health Institute)    		 Technical Consultant
    Cuernavaca, Mexico 2001 - 2002

    Developed direction and managed the implementation of internal and external computer resources for the health economics group. Worked in Spanish and English.

    Ariba Manager and Engineer
    Sunnyvale, California 1996 - 2001

    Member of original technical team that developed patented purchasing system. Worked on first six versions of released software. Managed team of programmers that implemented internationalization, management tools, and web applications.

    Netmarket (acquired by Cendant) Founder and Chief Programmer
    Cambridge, Massachusetts 1993 - 1996

    Co-founded software startup, hired engineers, and led software development efforts. Wrote software for first music CD store on the web, as featured in the New York Times.

    Swarthmore College Summer Researcher, Computer Science
    Swarthmore, Pennsylvania 1993

    Investigated the use of diagrams in developing proof plans for a natural deduction system.

    Nasa Ames Research Center Graphics Programmer
    Moffet Field, California 1990

    Conceived and produced animations and images for turbomachinery research group.

    Technical Skills

  • Programming Experience: statistical computing, client/server database, web programming, distributed computing.
  • Languages: Python, R, SQL, C, Ruby, Perl, MATLAB, LaTeX
  • Operating Systems: Unix (Linux, Solaris, OS X), Windows.

    • Interests and Skills

  • Activities and skills: Spanish proficiency, cooking (Certificate in Culinary Arts from the French Culinary Institute, New York City), classical guitar, and tennis.
  • Board member: San Francisco Works (previous), Mission Learning Center (previous).

    • References Available on request.